Quinolines and derivatives
Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 1 G
Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker that can be used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 4965-36-0 | 7-Bromoquinoline | Ambeed | MFCD03695823 | 208.058 | C9H6BrN | 98.000 | Brc1ccc2cccnc2c1 | 100g | 525125880
7-Bromoquinoline | Ambeed | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 98.000 | Brc1ccc2cccnc2c1 | 100g | 525125880
Medchemexpress LLC 4-Bromoisoquinoline | 1532-97-4 | MFCD00006904 | 98.7% | 208.05 | 25 G
4-Bromoisoquinoline is a biochemical reagent suitable for life science related research. It can be utilized as a biological material or an organic compound. This product is intended for research use only.
- Biochemical reagent
- Biological material or organic compound
- Suitable for life science related research
- For research use only
Medchemexpress LLC m-PEG7-amine | 170572-38-0 | MFCD13184965 | 98.0% | 339.43 g/mol | C15H33NO7 | 5 G
m-PEG7-Amine is a methoxy-terminated polyethylene glycol (PEG) linker bearing a terminal primary amine. It is used as a PROTAC linker and as a cleavable ADC linker for antibody-drug conjugation and other bioconjugation applications. The reagent provides a flexible, hydrophilic spacer suitable for linker chemistry in targeted degraders and conjugates.
- Methoxy-terminated PEG with seven ethylene glycol units.
- Terminal primary amine for facile coupling to carboxylates and activated esters.
- Molecular weight 339.43 g/mol and CAS 170572-38-0.
- Suitable for use as a PROTAC linker and a cleavable ADC linker.
- Hydrophilic spacer that improves solubility and reduces aggregation in conjugates.
eMolecules 873-42-7 | 3,5-dichloropyrazin-2-amine | Combi-Blocks | MFCD11040179 | 163.990 | C4H3Cl2N3 | 98.000 | Nc1ncc(Cl)nc1Cl | 5g | 232333226
3,5-dichloropyrazin-2-amine | Combi-Blocks | 873-42-7 | MFCD11040179 | 163.990 | C4H3Cl2N3 | 98.000 | Nc1ncc(Cl)nc1Cl | 5g | 232333226
Medchemexpress LLC Amine-PEG3-lys(PEG3-N3)-PEG3-N3 | 2244602-35-3 | 98.0% | 750.84 g/mol | C30H58N10O12 | 50 MG
Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 is a branched polyethylene glycol (PEG)-based linker with an amine terminus and azide functional groups. It is designed for use in antibody-drug conjugate (ADC) synthesis and general bioconjugation workflows where orthogonal azide chemistry and an amine handle are required.
- Branched PEG linker with amine and azide handles.
- Suitable for azide-alkyne click chemistry and amine coupling.
- High purity (98.0%).
- Available in multiple pack sizes, including 50 MG.
- Appearance: yellow to brown oil; stored at -20°C (pure) or -80°C in solvent for extended stability.
Medchemexpress LLC Azide-PEG-amine | 95.0% | 100 MG
Azide-PEG-amine (MW 5000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This molecule functions as a versatile click chemistry reagent, enabling crucial reactions in chemical biology and drug discovery.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
eMolecules 1368352-40-2 | ChemScene | 5-Bromo-4-ethylpyridin-2-amine | 100mg | 784458588 | CS-0334320 | MFCD22058625 | 201.067 | C7H9BrN2
Ambeed | (R)-2-Methylpiperidine | 250mg | 714088317 | A737468 | 1722-95-8 | MFCD01862168 | 99.177 | C6H13N
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Medchemexpress LLC Benzyl-PEG7-amine 25mg
Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Sulfo DBCO-amine | 2028284-70-8 | 99.0% | 100 MG
Sulfo DBCO-amine is an alkyl chain-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that possess Azide groups. PROTACs themselves are composed of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting a specific protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group for SPAAC with Azide groups
Medchemexpress LLC Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 | 2244602-35-3 | 98.0% | 750.84 g/mol | C30H58N10O12 | 10 MG
Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 is a branched polyethylene glycol (PEG)-based linker intended for use in the synthesis of antibody-drug conjugates (ADCs). It provides an amine reactive handle and multiple azide (N3) termini for bioconjugation, is supplied as a powder for research use, and has a reported molecular weight of 750.84 g/mol and purity of 98.0%.
- Branched PEG linker with multiple azide termini for orthogonal conjugation
- Amine reactive handle for straightforward coupling to biomolecules
- Compatible with click chemistry for ADC assembly
- High reported purity supports reproducible conjugation
- Stable when stored under recommended conditions
eMolecules 1128-61-6 | 6-fluoro-2-methylquinoline | Combi-Blocks, Inc. | MFCD00041233 | 161.179 | C10H8FN | 98.000 | Cc1ccc2cc(F)ccc2n1 | 25g | 586071561
6-fluoro-2-methylquinoline | Combi-Blocks, Inc. | 1128-61-6 | MFCD00041233 | 161.179 | C10H8FN | 98.000 | Cc1ccc2cc(F)ccc2n1 | 25g | 586071561
Medchemexpress LLC PEG-bis-amine (MW 20000) | 24991-53-5 | 98.0% | (C2H4O)nC4H12N2O | 250 MG
PEG-bis-amine (Poly(ethylene glycol)-bis-amine) (MW 20000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules employ the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting two ligands: one for an E3 ubiquitin ligase and another for the target protein. This compound appears as a white to off-white solid and has an average molecular weight of 20000. It is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- White to off-white solid appearance
- Average molecular weight of 20000
- Purity of 98.0%
- Soluble in water at 100 mg/mL (requires ultrasonic)
- Stable as powder at -20°C for 3 years
- Stable in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Mpeg-amine (MW 1000) | 80506-64-5 | 99.19% | (C2H4O)nC3H9NO | 100 MG
m-PEG-NH2 (MW 1000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates degradation of target proteins
- Utilizes the ubiquitin-proteasome system
Medchemexpress LLC 5-Bromoisoquinoline | 34784-04-8 | 208.058 | 1 G
5-Bromoisoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is also a synthetic intermediate useful for pharmaceutical synthesis.
- Used as a biochemical reagent
- Applicable as a biological material
- Suitable as an organic compound for life science research
- Functions as a synthetic intermediate for pharmaceuticals
- Store in a cool, dry, and well-ventilated place
- Keep container tightly closed